| 13. Round | 08/01/2022 | Crystal Palace [U18] | - | Norwich City [U18] | 0:0 | ||||
| 16. Round | 05/02/2022 | Tottenham Hotspur [U18] | - | Crystal Palace [U18] | 2:4 | ||||
| 17. Round | 19/02/2022 | Crystal Palace [U18] | - | Arsenal FC [U18] | 5:0 | ||||
| 18. Round | 26/02/2022 | Norwich City [U18] | - | Crystal Palace [U18] | 0:1 | ||||
| 19. Round | 05/03/2022 | Crystal Palace [U18] | - | Leicester City [U18] | 2:1 | ||||
| 20. Round | 11/03/2022 | West Ham United [U18] | - | Crystal Palace [U18] | 2:1 | ||||
| 21. Round | 19/03/2022 | West Bromwich Albion [U18] | - | Crystal Palace [U18] | 0:3 | ||||
| 22. Round | 02/04/2022 | Crystal Palace [U18] | - | Aston Villa [U18] | 6:1 | ||||
| 23. Round | 09/04/2022 | Southampton FC [U18] | - | Crystal Palace [U18] | 3:2 | ||||
| 12. Round | 12/04/2022 | Brighton & Hove Albion [U18] | - | Crystal Palace [U18] | 1:0 | ||||
| 24. Round | 23/04/2022 | Crystal Palace [U18] | - | Reading FC [U18] | 3:0 | ||||
| 25. Round | 30/04/2022 | Chelsea FC [U18] | - | Crystal Palace [U18] | 2:2 | ||||
| 26. Round | 07/05/2022 | Crystal Palace [U18] | - | Brighton & Hove Albion [U18] | 2:1 |  |
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| 14. Round | 14/05/2022 | Crystal Palace [U18] | - | Fulham FC [U18] | 1:0 |
England