| 1. Round | 13/08/2022 | Southampton FC [U18] | - | Aston Villa [U18] | 3:3 | ||||
| 2. Round | 20/08/2022 | West Ham United [U18] | - | Southampton FC [U18] | 4:1 | ||||
| 3. Round | 27/08/2022 | Southampton FC [U18] | - | Chelsea FC [U18] | 2:2 |  |
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| 4. Round | 17/09/2022 | Crystal Palace [U18] | - | Southampton FC [U18] | 3:2 | ||||
| 5. Round | 01/10/2022 | Southampton FC [U18] | - | Fulham FC [U18] | 3:5 | ||||
| 7. Round | 29/10/2022 | Leicester City [U18] | - | Southampton FC [U18] | 1:6 | ||||
| 6. Round | 10/12/2022 | Southampton FC [U18] | - | Norwich City [U18] | 0:2 | ||||
| 14. Round | 28/01/2023 | Southampton FC [U18] | - | West Ham United [U18] | 2:1 | ||||
| 16. Round | 18/02/2023 | Southampton FC [U18] | - | Tottenham Hotspur [U18] | 0:1 | ||||
| 17. Round | 25/02/2023 | West Bromwich Albion [U18] | - | Southampton FC [U18] | 0:1 | ||||
| 18. Round | 18/03/2023 | Chelsea FC [U18] | - | Southampton FC [U18] | 5:2 | |
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| 19. Round | 01/04/2023 | Southampton FC [U18] | - | Crystal Palace [U18] | 1:7 |
England