| 15. Round | 10/02/2023 | Southampton FC U21 | - | Sunderland AFC U21 | 2:2 | ||||
| 16. Round | 20/02/2023 | West Bromwich Albion U21 | - | Southampton FC U21 | 1:2 | ||||
| 5. Round | 31/03/2023 | Derby County U21 | - | Southampton FC U21 | 1:3 | ||||
| 21. Round | 14/04/2023 | Southampton FC U21 | - | Stoke City U21 | 2:0 | ||||
| 22. Round | 23/04/2023 | Norwich City U21 | - | Southampton FC U21 | 2:5 |
England