| 1. Round | 28/08/2022 | Sassuolo Calcio [Women] | - | UC Sampdoria [Women] | 1:2 |  |
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| 2. Round | 11/09/2022 | UC Sampdoria [Women] | - | Pomigliano CF [Women] | 2:1 | ||||
| 3. Round | 18/09/2022 | FC Como Women [Women] | - | UC Sampdoria [Women] | 0:1 | |
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| 4. Round | 25/09/2022 | UC Sampdoria [Women] | - | Inter [Women] | 0:2 | ||||
| 5. Round | 01/10/2022 | AC Milan [Women] | - | UC Sampdoria [Women] | 2:1 | ||||
| 6. Round | 16/10/2022 | UC Sampdoria [Women] | - | Juventus [Women] | 0:4 | ||||
| 7. Round | 23/10/2022 | ACF Fiorentina [Women] | - | UC Sampdoria [Women] | 2:1 | |
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| 8. Round | 30/10/2022 | UC Sampdoria [Women] | - | Parma Calcio 1913 [Women] | 0:0 | |
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| 9. Round | 19/11/2022 | AS Roma [Women] | - | UC Sampdoria [Women] | 2:0 | ||||
| 14. Round | 21/01/2023 | UC Sampdoria [Women] | - | AC Milan [Women] | 0:3 |
France