| 25. Round | 03/04/2021 | Madrid CFF [Women] | - | UDG Tenerife Sur [Women] | 2:4 | ||||
| 26. Round | 17/04/2021 | Valencia CF [Women] | - | Madrid CFF [Women] | 2:0 | ||||
| 27. Round | 25/04/2021 | Madrid CFF [Women] | - | Real Madrid [Women] | 0:2 | ||||
| 15. Round | 28/04/2021 | Madrid CFF [Women] | - | FC Barcelona [Women] | 0:2 | ||||
| 28. Round | 02/05/2021 | Deportivo La Coruña [Women] | - | Madrid CFF [Women] | 3:0 |  |
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| 29. Round | 09/05/2021 | Madrid CFF [Women] | - | Atlético Madrid [Women] | 0:1 | ||||
| 30. Round | 15/05/2021 | Sevilla FC [Women] | - | Madrid CFF [Women] | 0:1 | ||||
| 31. Round | 22/05/2021 | Madrid CFF [Women] | - | Levante UD [Women] | 2:3 | ||||
| 33. Round | 19/06/2021 | Espanyol Barcelona [Women] | - | Madrid CFF [Women] | 3:3 | |
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| 34. Round | 27/06/2021 | Madrid CFF [Women] | - | Real Betis [Women] | 2:2 |  |
Brazil