| 1. Round | 13/08/2021 | Aston Villa U23 | - | Nottingham Forest U23 | 5:2 | ||||
| 2. Round | 20/08/2021 | Middlesbrough FC U23 | - | Aston Villa U23 | 1:2 |  |
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| 3. Round | 27/08/2021 | Aston Villa U23 | - | Fulham FC U23 | 1:1 | ||||
| 4. Round | 10/09/2021 | Norwich City U23 | - | Aston Villa U23 | 4:2 | |
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| 5. Round | 17/09/2021 | Aston Villa U23 | - | West Bromwich Albion U23 | 4:2 | ||||
| 6. Round | 27/09/2021 | Stoke City U23 | - | Aston Villa U23 | 0:8 | ||||
| 7. Round | 01/10/2021 | Aston Villa U23 | - | Wolverhampton Wanderers U23 | 0:0 | |
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| 8. Round | 16/10/2021 | Birmingham City U23 | - | Aston Villa U23 | 1:2 | ||||
| 9. Round | 22/10/2021 | Aston Villa U23 | - | Sunderland AFC U23 | 2:3 | ||||
| 12. Round | 22/11/2021 | Aston Villa U23 | - | Burnley FC U23 | 4:1 |
Netherlands
Suriname