8. Round 18/09/2021 Tranmere Rovers - Salford City 2:0
10. Round 02/10/2021 Tranmere Rovers - Crawley Town 2:1
12. Round 16/10/2021 Carlisle United - Tranmere Rovers 0:1
17. Round 20/11/2021 Bristol Rovers - Tranmere Rovers 2:2
18. Round 23/11/2021 Tranmere Rovers - Bradford City 2:1
20. Round 07/12/2021 Oldham Athletic - Tranmere Rovers 0:1
21. Round 11/12/2021 Exeter City - Tranmere Rovers 0:1
22. Round 18/12/2021 Tranmere Rovers - Leyton Orient 1:0
23. Round 26/12/2021 Tranmere Rovers - Barrow AFC 2:0
26. Round 08/01/2022 Tranmere Rovers - Scunthorpe United 4:0 yellow card
25. Round 11/01/2022 Salford City - Tranmere Rovers 1:1
27. Round 15/01/2022 Tranmere Rovers - Rochdale AFC 2:0
28. Round 22/01/2022 Crawley Town - Tranmere Rovers 0:1
29. Round 29/01/2022 Tranmere Rovers - Forest Green Rovers 0:4
19. Round 01/02/2022 Tranmere Rovers - Stevenage FC 1:0
30. Round 05/02/2022 Barrow AFC - Tranmere Rovers 1:1
31. Round 08/02/2022 Tranmere Rovers - Swindon Town 3:0
32. Round 12/02/2022 Walsall FC - Tranmere Rovers 1:0
33. Round 19/02/2022 Tranmere Rovers - Port Vale FC 1:1
34. Round 26/02/2022 Newport County - Tranmere Rovers 4:2
35. Round 05/03/2022 Northampton Town - Tranmere Rovers 3:2 yellow card
36. Round 11/03/2022 Tranmere Rovers - Mansfield Town 3:2
37. Round 15/03/2022 Tranmere Rovers - Harrogate Town 2:0
38. Round 19/03/2022 Sutton United - Tranmere Rovers 1:1
40. Round 02/04/2022 Tranmere Rovers - Carlisle United 2:2
41. Round 09/04/2022 Tranmere Rovers - Bristol Rovers 1:1
42. Round 15/04/2022 Bradford City - Tranmere Rovers 1:1
43. Round 18/04/2022 Tranmere Rovers - Exeter City 2:0
44. Round 23/04/2022 Stevenage FC - Tranmere Rovers 2:0
45. Round 30/04/2022 Tranmere Rovers - Oldham Athletic 2:0 yellow card
46. Round 07/05/2022 Leyton Orient - Tranmere Rovers 0:1 yellow card