| 1. Round | 30/07/2022 | Cambridge United | - | Milton Keynes Dons | 1:0 | ||||
| 2. Round | 06/08/2022 | Oxford United | - | Cambridge United | 1:0 | ||||
| 3. Round | 13/08/2022 | Cambridge United | - | Exeter City | 2:1 | ||||
| 4. Round | 16/08/2022 | Portsmouth FC | - | Cambridge United | 4:1 |  |
|||
| 6. Round | 27/08/2022 | Cambridge United | - | Burton Albion | 4:3 |  |
|||
| 7. Round | 03/09/2022 | Cambridge United | - | Lincoln City | 2:0 | ||||
| 9. Round | 13/09/2022 | Cheltenham Town | - | Cambridge United | 2:1 | ||||
| 10. Round | 17/09/2022 | Cambridge United | - | Barnsley FC | 0:3 | ||||
| 8. Round | 04/10/2022 | Ipswich Town | - | Cambridge United | 3:0 | ||||
| 14. Round | 08/10/2022 | Bristol Rovers | - | Cambridge United | 2:1 | ||||
| 16. Round | 22/10/2022 | Cambridge United | - | Port Vale FC | 0:1 | ||||
| 17. Round | 29/10/2022 | Peterborough United | - | Cambridge United | 1:0 | |
|||
| 34. Round | 25/02/2023 | Exeter City | - | Cambridge United | 2:0 | ||||
| 35. Round | 04/03/2023 | Cambridge United | - | Portsmouth FC | 0:1 | ||||
| 27. Round | 07/03/2023 | Cambridge United | - | Morecambe FC | 1:1 | ||||
| 36. Round | 11/03/2023 | Milton Keynes Dons | - | Cambridge United | 1:0 | ||||
| 38. Round | 03/05/2023 | Burton Albion | - | Cambridge United | 1:0 |
England