1. Round 07/08/2021 Charlton Athletic - Sheffield Wednesday 0:0
2. Round 14/08/2021 Sheffield Wednesday - Doncaster Rovers 2:0
3. Round 17/08/2021 Sheffield Wednesday - Fleetwood Town 1:0
4. Round 21/08/2021 Rotherham United - Sheffield Wednesday 0:2
5. Round 28/08/2021 Morecambe FC - Sheffield Wednesday 1:0
7. Round 11/09/2021 Plymouth Argyle - Sheffield Wednesday 3:0
8. Round 18/09/2021 Sheffield Wednesday - Shrewsbury Town 1:1
9. Round 25/09/2021 Ipswich Town - Sheffield Wednesday 1:1
10. Round 28/09/2021 Wigan Athletic - Sheffield Wednesday 1:2
11. Round 02/10/2021 Sheffield Wednesday - Oxford United 1:2 yellow card
12. Round 09/10/2021 Sheffield Wednesday - Bolton Wanderers 1:0
13. Round 16/10/2021 AFC Wimbledon - Sheffield Wednesday 2:2
14. Round 19/10/2021 Cambridge United - Sheffield Wednesday 1:1 yellow card
15. Round 23/10/2021 Sheffield Wednesday - Lincoln City 1:1
16. Round 30/10/2021 Cheltenham Town - Sheffield Wednesday 2:2
6. Round 02/11/2021 Sheffield Wednesday - Sunderland AFC 3:0
17. Round 13/11/2021 Sheffield Wednesday - Gillingham FC 1:1
18. Round 20/11/2021 Accrington Stanley - Sheffield Wednesday 2:3
19. Round 23/11/2021 Sheffield Wednesday - Milton Keynes Dons 2:1 yellow card
21. Round 07/12/2021 Portsmouth FC - Sheffield Wednesday 0:0
22. Round 11/12/2021 Crewe Alexandra - Sheffield Wednesday 0:2
25. Round 30/12/2021 Sunderland AFC - Sheffield Wednesday 5:0
26. Round 02/01/2022 Shrewsbury Town - Sheffield Wednesday 1:0
28. Round 15/01/2022 Sheffield Wednesday - Plymouth Argyle 4:2
29. Round 22/01/2022 Oxford United - Sheffield Wednesday 3:2
30. Round 29/01/2022 Sheffield Wednesday - Ipswich Town 1:0
27. Round 01/02/2022 Sheffield Wednesday - Morecambe FC 2:0
31. Round 05/02/2022 Burton Albion - Sheffield Wednesday 0:2
32. Round 08/02/2022 Sheffield Wednesday - Wigan Athletic 1:0
33. Round 13/02/2022 Sheffield Wednesday - Rotherham United 0:2
34. Round 19/02/2022 Doncaster Rovers - Sheffield Wednesday 1:3
36. Round 26/02/2022 Sheffield Wednesday - Charlton Athletic 2:0 yellow card
24. Round 01/03/2022 Sheffield Wednesday - Burton Albion 5:2 Goal
37. Round 05/03/2022 Lincoln City - Sheffield Wednesday 3:1
23. Round 15/03/2022 Sheffield Wednesday - Accrington Stanley 1:1
43. Round 16/04/2022 Milton Keynes Dons - Sheffield Wednesday 2:3 yellow card
44. Round 19/04/2022 Sheffield Wednesday - Crewe Alexandra 1:0
35. Round 26/04/2022 Fleetwood Town - Sheffield Wednesday 2:3
46. Round 30/04/2022 Sheffield Wednesday - Portsmouth FC 4:1