| 22. Round | 30/01/2021 | King's Lynn | - | Wrexham AFC | 0:2 | ||||
| 14. Round | 02/02/2021 | Eastleigh FC | - | Wrexham AFC | 1:1 | ||||
| 23. Round | 06/02/2021 | Wrexham AFC | - | Dagenham & Redbridge | 2:2 | ||||
| 24. Round | 09/02/2021 | Altrincham FC | - | Wrexham AFC | 1:2 | ||||
| 19. Round | 16/02/2021 | Wrexham AFC | - | Woking FC | 2:0 | ||||
| 26. Round | 20/02/2021 | Aldershot Town | - | Wrexham AFC | 3:0 | ||||
| 27. Round | 23/02/2021 | Wrexham AFC | - | Hartlepool United | 0:0 | ||||
| 28. Round | 27/02/2021 | Wrexham AFC | - | Wealdstone FC | 4:1 | ||||
| 29. Round | 06/03/2021 | Sutton United | - | Wrexham AFC | 0:0 | ||||
| 30. Round | 09/03/2021 | Barnet FC | - | Wrexham AFC | 0:2 | ||||
| 31. Round | 13/03/2021 | Wrexham AFC | - | Weymouth FC | 2:0 | ||||
| 32. Round | 16/03/2021 | Wrexham AFC | - | Eastleigh FC | 2:2 | ||||
| 34. Round | 27/03/2021 | Wrexham AFC | - | Bromley FC | 3:0 | ||||
| 36. Round | 05/04/2021 | Wrexham AFC | - | Torquay United | 0:1 | ||||
| 37. Round | 10/04/2021 | Wrexham AFC | - | Stockport County | 0:3 | ||||
| 38. Round | 13/04/2021 | Halifax Town | - | Wrexham AFC | 0:4 | ||||
| 39. Round | 17/04/2021 | Woking FC | - | Wrexham AFC | 0:4 |  |
England