| 1. Round | 06/08/2005 | Crewe Alexandra | - | Burnley FC | 2:1 | ||||
| 2. Round | 09/08/2005 | Norwich City | - | Crewe Alexandra | 1:1 | ||||
| 3. Round | 13/08/2005 | Brighton & Hove Albion | - | Crewe Alexandra | 2:2 |  |
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| 4. Round | 20/08/2005 | Crewe Alexandra | - | Leicester City | 2:2 | |
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| 5. Round | 27/08/2005 | Southampton FC | - | Crewe Alexandra | 2:0 | ||||
| 7. Round | 11/09/2005 | Crewe Alexandra | - | Derby County | 1:1 | |
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| 8. Round | 13/09/2005 | Plymouth Argyle | - | Crewe Alexandra | 1:1 | ||||
| 9. Round | 17/09/2005 | Reading FC | - | Crewe Alexandra | 1:0 | ||||
| 10. Round | 24/09/2005 | Crewe Alexandra | - | Watford FC | 0:0 | ||||
| 12. Round | 01/10/2005 | Ipswich Town | - | Crewe Alexandra | 2:1 | ||||
| 13. Round | 15/10/2005 | Crewe Alexandra | - | Luton Town | 3:1 | ||||
| 15. Round | 22/10/2005 | Cardiff City | - | Crewe Alexandra | 6:1 | ||||
| 16. Round | 29/10/2005 | Crewe Alexandra | - | Crystal Palace | 2:2 | ||||
| 19. Round | 19/11/2005 | Crewe Alexandra | - | Stoke City | 1:2 | ||||
| 20. Round | 22/11/2005 | Luton Town | - | Crewe Alexandra | 4:1 | ||||
| 21. Round | 26/11/2005 | Burnley FC | - | Crewe Alexandra | 3:0 | ||||
| 29. Round | 14/01/2006 | Derby County | - | Crewe Alexandra | 5:1 |
England