| 1. Round | 30/07/2022 | Lincoln City | - | Exeter City | 1:1 | ||||
| 2. Round | 06/08/2022 | Exeter City | - | Port Vale FC | 4:0 | ||||
| 3. Round | 13/08/2022 | Cambridge United | - | Exeter City | 2:1 | ||||
| 4. Round | 16/08/2022 | Exeter City | - | Wycombe Wanderers | 3:1 | ||||
| 5. Round | 20/08/2022 | Exeter City | - | Cheltenham Town | 0:1 | ||||
| 6. Round | 27/08/2022 | Accrington Stanley | - | Exeter City | 0:0 | ||||
| 9. Round | 13/09/2022 | Shrewsbury Town | - | Exeter City | 3:2 | ||||
| 10. Round | 17/09/2022 | Exeter City | - | Burton Albion | 0:2 | ||||
| 11. Round | 24/09/2022 | Forest Green Rovers | - | Exeter City | 0:4 | ||||
| 15. Round | 15/10/2022 | Exeter City | - | Oxford United | 2:4 | ||||
| 16. Round | 22/10/2022 | Exeter City | - | Fleetwood Town | 2:1 | ||||
| 13. Round | 25/10/2022 | Derby County | - | Exeter City | 0:0 |  |
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| 17. Round | 31/10/2022 | Plymouth Argyle | - | Exeter City | 4:2 | ||||
| 18. Round | 12/11/2022 | Exeter City | - | Peterborough United | 3:2 | ||||
| 19. Round | 19/11/2022 | Exeter City | - | Ipswich Town | 0:2 | ||||
| 22. Round | 17/12/2022 | Bolton Wanderers | - | Exeter City | 2:0 | ||||
| 23. Round | 26/12/2022 | Exeter City | - | Portsmouth FC | 0:0 | ||||
| 24. Round | 29/12/2022 | Bristol Rovers | - | Exeter City | 3:4 |
England