| 10. Round | 14/12/2024 | Manchester United U21 | - | Southampton FC U21 | 5:1 | ||||
| 11. Round | 10/01/2025 | Southampton FC U21 | - | Fulham FC U21 | 5:0 | ||||
| 13. Round | 24/01/2025 | Chelsea FC U21 | - | Southampton FC U21 | 0:2 | ||||
| 14. Round | 07/02/2025 | Southampton FC U21 | - | Liverpool FC U21 | 1:1 |  |
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| 15. Round | 14/02/2025 | Everton FC U21 | - | Southampton FC U21 | 1:2 | ||||
| 16. Round | 21/02/2025 | Southampton FC U21 | - | Sunderland AFC U21 | 3:3 |  |
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| 17. Round | 28/02/2025 | Southampton FC U21 | - | Wolverhampton Wanderers U21 | 2:1 |
England