| 1. Round | 13/09/2020 | Sparta Rotterdam | - | AFC Ajax | 0:1 | ||||
| 2. Round | 20/09/2020 | AFC Ajax | - | RKC Waalwijk | 3:0 | ||||
| 3. Round | 26/09/2020 | AFC Ajax | - | Vitesse | 2:1 | ||||
| 4. Round | 04/10/2020 | FC Groningen | - | AFC Ajax | 1:0 | ||||
| 5. Round | 18/10/2020 | AFC Ajax | - | sc Heerenveen | 5:1 | ||||
| 7. Round | 31/10/2020 | AFC Ajax | - | Fortuna Sittard | 5:2 | ||||
| 8. Round | 08/11/2020 | FC Utrecht | - | AFC Ajax | 0:3 | ||||
| 9. Round | 22/11/2020 | AFC Ajax | - | Heracles Almelo | 5:0 | ||||
| 10. Round | 28/11/2020 | FC Emmen | - | AFC Ajax | 0:5 | ||||
| 15. Round | 10/01/2021 | AFC Ajax | - | PSV Eindhoven | 2:2 | ||||
| 16. Round | 14/01/2021 | FC Twente | - | AFC Ajax | 1:3 | ||||
| 17. Round | 17/01/2021 | AFC Ajax | - | Feyenoord | 1:0 | ||||
| 18. Round | 24/01/2021 | Fortuna Sittard | - | AFC Ajax | 1:2 | ||||
| 19. Round | 28/01/2021 | AFC Ajax | - | Willem II | 3:1 | ||||
| 22. Round | 13/02/2021 | Heracles Almelo | - | AFC Ajax | 0:2 | ||||
| 21. Round | 22/04/2021 | AFC Ajax | - | FC Utrecht | 1:1 | ||||
| 30. Round | 25/04/2021 | AFC Ajax | - | AZ Alkmaar | 2:0 | ||||
| 31. Round | 02/05/2021 | AFC Ajax | - | FC Emmen | 4:0 | ||||
| 32. Round | 09/05/2021 | Feyenoord | - | AFC Ajax | 0:3 |
Netherlands
