| 20. Round | 24/12/1921 | Everton FC | - | Manchester City | 2:2 | ||||
| 21. Round | 26/12/1921 | Huddersfield Town | - | Manchester City | 2:0 | ||||
| 23. Round | 31/12/1921 | Manchester City | - | Sunderland AFC | 3:0 | ||||
| 22. Round | 02/01/1922 | Manchester City | - | Huddersfield Town | 2:1 |  |
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| 24. Round | 14/01/1922 | Sunderland AFC | - | Manchester City | 2:3 | ||||
| 25. Round | 21/01/1922 | Manchester City | - | Middlesbrough FC | 2:2 | ||||
| 26. Round | 01/02/1922 | Middlesbrough FC | - | Manchester City | 4:1 | ||||
| 27. Round | 04/02/1922 | Manchester City | - | Tottenham Hotspur | 3:3 | ||||
| 28. Round | 11/02/1922 | Tottenham Hotspur | - | Manchester City | 3:1 | ||||
| 29. Round | 22/02/1922 | Manchester City | - | Bradford City | 3:2 | ||||
| 33. Round | 18/03/1922 | Chelsea FC | - | Manchester City | 0:0 |
Northern Ireland
All Ireland