| 3. Round | 22/08/1980 | Stoke City | - | Ipswich Town | 2:2 | ||||
| 4. Round | 29/08/1980 | Nottingham Forest | - | Stoke City | 5:0 | ||||
| 9. Round | 04/10/1980 | Stoke City | - | Tottenham Hotspur | 2:3 | ||||
| 14. Round | 25/10/1980 | Birmingham City | - | Stoke City | 1:1 | ||||
| 15. Round | 31/10/1980 | Stoke City | - | Liverpool FC | 2:2 |  |
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| 16. Round | 07/11/1980 | Sunderland AFC | - | Stoke City | 0:0 | ||||
| 17. Round | 24/11/1980 | West Bromwich Albion | - | Stoke City | 0:0 | ||||
| 23. Round | 12/12/1980 | Manchester United | - | Stoke City | 2:2 | |
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| 22. Round | 19/12/1980 | Stoke City | - | Leicester City | 1:0 | ||||
| 24. Round | 25/12/1980 | Aston Villa | - | Stoke City | 1:0 |
England