| 1. Round | 08/08/2015 | Accrington Stanley | - | Luton Town | 1:1 | ||||
| 2. Round | 15/08/2015 | Luton Town | - | Oxford United | 2:2 | ||||
| 3. Round | 18/08/2015 | Luton Town | - | Bristol Rovers | 0:1 | ||||
| 4. Round | 22/08/2015 | Yeovil Town | - | Luton Town | 3:2 | ||||
| 5. Round | 29/08/2015 | Luton Town | - | Portsmouth FC | 1:2 | ||||
| 6. Round | 05/09/2015 | Cambridge United | - | Luton Town | 1:3 | ||||
| 7. Round | 12/09/2015 | Notts County | - | Luton Town | 3:2 | ||||
| 8. Round | 19/09/2015 | Luton Town | - | Mansfield Town | 1:0 | ||||
| 9. Round | 26/09/2015 | Luton Town | - | AFC Wimbledon | 2:0 | ||||
| 10. Round | 29/09/2015 | Morecambe FC | - | Luton Town | 1:3 | ||||
| 11. Round | 03/10/2015 | Hartlepool United | - | Luton Town | 1:4 | ||||
| 16. Round | 01/11/2015 | Dagenham & Redbridge | - | Luton Town | 0:2 | ||||
| 17. Round | 14/11/2015 | Luton Town | - | Barnet FC | 2:0 | ||||
| 18. Round | 21/11/2015 | Stevenage FC | - | Luton Town | 0:0 | ||||
| 19. Round | 24/11/2015 | Luton Town | - | Carlisle United | 3:4 | ||||
| 20. Round | 28/11/2015 | Newport County | - | Luton Town | 3:0 | ||||
| 21. Round | 12/12/2015 | Luton Town | - | Northampton Town | 3:4 |  |
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| 22. Round | 19/12/2015 | Exeter City | - | Luton Town | 2:3 |
England