| 1. Round | 07/08/2010 | Crewe Alexandra | - | Hereford United | 0:1 | ||||
| 2. Round | 14/08/2010 | Hereford United | - | Gillingham FC | 0:0 | ||||
| 3. Round | 21/08/2010 | Chesterfield FC | - | Hereford United | 4:0 |  |
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| 4. Round | 28/08/2010 | Hereford United | - | Rotherham United | 0:1 | |
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| 6. Round | 11/09/2010 | Hereford United | - | Oxford United | 0:2 | ||||
| 7. Round | 18/09/2010 | Bury FC | - | Hereford United | 1:1 | ||||
| 9. Round | 28/09/2010 | Hereford United | - | Stevenage FC | 1:4 |  |
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| 10. Round | 02/10/2010 | Barnet FC | - | Hereford United | 2:0 | ||||
| 11. Round | 09/10/2010 | Hereford United | - | Port Vale FC | 1:1 | |
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| 13. Round | 23/10/2010 | Hereford United | - | Accrington Stanley | 1:1 | ||||
| 16. Round | 13/11/2010 | Hereford United | - | Cheltenham Town | 1:1 | ||||
| 17. Round | 20/11/2010 | Lincoln City | - | Hereford United | 3:1 | ||||
| 18. Round | 23/11/2010 | Shrewsbury Town | - | Hereford United | 4:0 | ||||
| 27. Round | 15/01/2011 | Hereford United | - | Stockport County | 3:0 | ||||
| 30. Round | 01/02/2011 | Torquay United | - | Hereford United | 1:3 | ||||
| 31. Round | 05/02/2011 | Hereford United | - | Lincoln City | 0:1 |
England