| 1. Round | 05/08/2022 | Everton FC U21 | - | Blackburn Rovers U21 | 2:0 | ||||
| 2. Round | 12/08/2022 | Tottenham Hotspur U21 | - | Everton FC U21 | 0:2 | ||||
| 3. Round | 19/08/2022 | Everton FC U21 | - | Manchester United U21 | 2:2 | ||||
| 4. Round | 27/08/2022 | West Ham United U21 | - | Everton FC U21 | 1:2 | ||||
| 5. Round | 03/09/2022 | Everton FC U21 | - | Chelsea FC U21 | 0:2 | ||||
| 7. Round | 18/09/2022 | Everton FC U21 | - | Brighton & Hove Albion U21 | 1:0 |  |
|||
| 8. Round | 30/09/2022 | Fulham FC U21 | - | Everton FC U21 | 2:0 | ||||
| 9. Round | 09/10/2022 | Crystal Palace U21 | - | Everton FC U21 | 3:4 | ||||
| 11. Round | 22/10/2022 | Liverpool FC U21 | - | Everton FC U21 | 2:1 | ||||
| 12. Round | 29/10/2022 | Everton FC U21 | - | Manchester City U21 | 6:3 | |
|||
| 13. Round | 06/11/2022 | Arsenal FC U21 | - | Everton FC U21 | 3:1 | ||||
| 14. Round | 06/01/2023 | Everton FC U21 | - | West Ham United U21 | 1:2 | ||||
| 15. Round | 15/01/2023 | Blackburn Rovers U21 | - | Everton FC U21 | 4:2 | |
England