| 1. Round | 12/09/2020 | Lincoln City | - | Oxford United | 2:0 | ||||
| 2. Round | 19/09/2020 | Oxford United | - | Sunderland AFC | 0:2 | ||||
| 3. Round | 26/09/2020 | Accrington Stanley | - | Oxford United | 1:4 | ||||
| 5. Round | 10/10/2020 | Gillingham FC | - | Oxford United | 3:1 | ||||
| 6. Round | 17/10/2020 | Peterborough United | - | Oxford United | 2:0 | ||||
| 7. Round | 20/10/2020 | Oxford United | - | Milton Keynes Dons | 3:2 | ||||
| 9. Round | 27/10/2020 | Charlton Athletic | - | Oxford United | 2:0 | ||||
| 10. Round | 31/10/2020 | Fleetwood Town | - | Oxford United | 2:0 | ||||
| 11. Round | 03/11/2020 | Oxford United | - | Rochdale AFC | 3:1 | ||||
| 4. Round | 17/11/2020 | Oxford United | - | Crewe Alexandra | 0:2 | ||||
| 13. Round | 21/11/2020 | Wigan Athletic | - | Oxford United | 1:2 | ||||
| 14. Round | 24/11/2020 | Portsmouth FC | - | Oxford United | 1:1 | ||||
| 8. Round | 28/11/2020 | Oxford United | - | Swindon Town | 1:2 |  |
England
