| 3. Round | 04/09/1920 | Huddersfield Town | - | Preston North End | 1:0 | ||||
| 4. Round | 06/09/1920 | Preston North End | - | Middlesbrough FC | 2:0 |  |
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| 5. Round | 11/09/1920 | Newcastle United | - | Preston North End | 4:2 | |
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| 10. Round | 16/10/1920 | Preston North End | - | Aston Villa | 6:1 | |
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| 11. Round | 23/10/1920 | Manchester United | - | Preston North End | 1:0 | ||||
| 12. Round | 30/10/1920 | Preston North End | - | Manchester United | 0:0 | ||||
| 13. Round | 06/11/1920 | Chelsea FC | - | Preston North End | 1:1 | ||||
| 14. Round | 13/11/1920 | Preston North End | - | Chelsea FC | 0:1 | ||||
| 15. Round | 20/11/1920 | Tottenham Hotspur | - | Preston North End | 1:2 | |
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| 16. Round | 27/11/1920 | Preston North End | - | Tottenham Hotspur | 4:1 | |
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| 17. Round | 04/12/1920 | Oldham Athletic | - | Preston North End | 0:2 | |
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| 19. Round | 18/12/1920 | Burnley FC | - | Preston North End | 2:0 | ||||
| 22. Round | 01/01/1921 | Preston North End | - | Burnley FC | 0:3 |
Wales