| 8. Round | 24/10/2020 | Blackpool FC | - | Milton Keynes Dons | 1:0 | ||||
| 9. Round | 27/10/2020 | Milton Keynes Dons | - | Wigan Athletic | 2:0 |  |
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| 10. Round | 31/10/2020 | Milton Keynes Dons | - | AFC Wimbledon | 1:1 | ||||
| 11. Round | 03/11/2020 | Northampton Town | - | Milton Keynes Dons | 0:0 | ||||
| 12. Round | 14/11/2020 | Sunderland AFC | - | Milton Keynes Dons | 1:2 | ||||
| 13. Round | 21/11/2020 | Milton Keynes Dons | - | Hull City | 1:3 | |
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| 14. Round | 24/11/2020 | Milton Keynes Dons | - | Shrewsbury Town | 2:2 | ||||
| 15. Round | 02/12/2020 | Charlton Athletic | - | Milton Keynes Dons | 0:1 | ||||
| 16. Round | 05/12/2020 | Accrington Stanley | - | Milton Keynes Dons | 2:1 | ||||
| 17. Round | 12/12/2020 | Milton Keynes Dons | - | Burton Albion | 1:1 | ||||
| 18. Round | 15/12/2020 | Milton Keynes Dons | - | Peterborough United | 1:1 | ||||
| 19. Round | 19/12/2020 | Plymouth Argyle | - | Milton Keynes Dons | 1:0 |
England