| 19. Round | 27/12/1909 | The Wednesday FC | - | Manchester United | 4:1 | ||||
| 21. Round | 08/01/1910 | Bury FC | - | Manchester United | 1:1 | ||||
| 22. Round | 22/01/1910 | Manchester United | - | Tottenham Hotspur | 5:0 |  |
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| 27. Round | 26/02/1910 | Aston Villa | - | Manchester United | 7:1 | ||||
| 28. Round | 05/03/1910 | Manchester United | - | Sheffield United | 1:0 | ||||
| 34. Round | 02/04/1910 | Manchester United | - | Blackburn Rovers | 2:0 | ||||
| 37. Round | 23/04/1910 | Everton FC | - | Manchester United | 3:3 | ||||
| 38. Round | 30/04/1910 | Manchester United | - | Middlesbrough FC | 4:1 |
England