| 3. Round | 28/09/2020 | Everton FC U23 | - | Derby County U23 | 4:1 | ||||
| 6. Round | 23/10/2020 | Manchester United U23 | - | Everton FC U23 | 2:1 | ||||
| 9. Round | 20/11/2020 | Arsenal FC U23 | - | Everton FC U23 | 1:0 | ||||
| 14. Round | 18/01/2021 | Everton FC U23 | - | Liverpool FC U23 | 1:1 | ||||
| 15. Round | 25/01/2021 | Leicester City U23 | - | Everton FC U23 | 2:4 | ||||
| 16. Round | 01/02/2021 | Derby County U23 | - | Everton FC U23 | 1:3 | ||||
| 17. Round | 05/02/2021 | Manchester City U23 | - | Everton FC U23 | 3:1 |  |
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| 18. Round | 05/03/2021 | Tottenham Hotspur U23 | - | Everton FC U23 | 2:1 | ||||
| 21. Round | 12/03/2021 | Chelsea FC U23 | - | Everton FC U23 | 2:1 | ||||
| 22. Round | 21/03/2021 | Everton FC U23 | - | Arsenal FC U23 | 1:1 | ||||
| 23. Round | 09/04/2021 | Everton FC U23 | - | Blackburn Rovers U23 | 2:1 | ||||
| 24. Round | 19/04/2021 | West Ham United U23 | - | Everton FC U23 | 2:1 | ||||
| 26. Round | 02/05/2021 | Southampton FC U23 | - | Everton FC U23 | 0:5 | |
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| 13. Round | 07/05/2021 | Everton FC U23 | - | Southampton FC U23 | 4:0 |
England