16. Round | 04/02/2022 | Aston Villa [U18] | - | Southampton FC [U18] | 0:5 | ||||
17. Round | 19/02/2022 | Southampton FC [U18] | - | West Bromwich Albion [U18] | 2:1 | ||||
18. Round | 26/02/2022 | Fulham FC [U18] | - | Southampton FC [U18] | 2:3 | ||||
19. Round | 05/03/2022 | Southampton FC [U18] | - | Norwich City [U18] | 5:0 | ||||
20. Round | 12/03/2022 | Birmingham City [U18] | - | Southampton FC [U18] | 1:4 | ||||
21. Round | 19/03/2022 | Southampton FC [U18] | - | West Ham United [U18] | 0:0 | ||||
22. Round | 02/04/2022 | Arsenal FC [U18] | - | Southampton FC [U18] | 4:2 |