2. Round | 14/08/2021 | Barrow AFC | - | Hartlepool United | 3:2 | ||||
4. Round | 21/08/2021 | Hartlepool United | - | Walsall FC | 2:0 | ||||
5. Round | 28/08/2021 | Hartlepool United | - | Carlisle United | 2:1 | ||||
6. Round | 04/09/2021 | Tranmere Rovers | - | Hartlepool United | 1:0 | ||||
7. Round | 11/09/2021 | Hartlepool United | - | Bristol Rovers | 1:0 | ||||
3. Round | 14/09/2021 | Sutton United | - | Hartlepool United | 1:0 | ||||
10. Round | 02/10/2021 | Stevenage FC | - | Hartlepool United | 2:0 | ||||
11. Round | 09/10/2021 | Hartlepool United | - | Northampton Town | 2:1 | ||||
12. Round | 16/10/2021 | Salford City | - | Hartlepool United | 2:0 | ||||
19. Round | 27/11/2021 | Port Vale FC | - | Hartlepool United | 2:0 |