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| 09/01/2023 | 19:00 | Watford FC | - | Everton FC | 3:1 (1:0) | |
| 10/01/2023 | 19:45 | Oxford United | - | Cardiff City | 3:1 (0:1) | |
| 11/01/2023 | 19:00 | Stoke City | - | Manchester United | 1:0 (0:0) | |
| 19:00 | Port Vale FC | - | Liverpool FC | 0:1 (0:1) | ||
| 13/01/2023 | 19:00 | Sheffield Wednesday | - | Leicester City | 3:2 (1:2) | |
| 17/01/2023 | 14:00 | Aston Villa | - | Southampton FC | 1:4 (0:1) | |
| 19:00 | Newcastle United | - | Arsenal FC | 2:3 (1:2) | ||
| 19:00 | Manchester City | - | Brighton & Hove Albion | 4:1 (2:1) | ||
| 19:00 | Ipswich Town | - | Nottingham Forest | 4:2 (0:1, 1:1, 1:1) pso | ||
| 18/01/2023 | 19:00 | Luton Town | - | Queens Park Rangers | 3:1 (2:1) | |
| 19:00 | Gillingham FC | - | Preston North End | 1:2 (1:1) | ||
| 19:00 | Fleetwood Town | - | Middlesbrough FC | 3:0 (1:0) | ||
| 24/01/2023 | 19:00 | Burnley FC | - | West Ham United | 0:1 (0:0) | |
| 25/01/2023 | 19:00 | Sunderland AFC | - | Fulham FC | 0:2 (0:1) | |
| 26/01/2023 | 19:00 | Cambridge United | - | Chelsea FC | 1:0 (1:0) | |
| 01/02/2023 | 19:00 | AFC Wimbledon | - | Leeds United | 1:3 (1:1, 1:1) aet |
