| FA Cup | M. | W | D | L | goals | |||
| at home | 1 | 0 | 1 | 0 | 1 | : | 1 | |
| Away | 2 | 1 | 0 | 1 | 5 | : | 5 | |
| ∑ | 3 | 1 | 1 | 1 | 6 | : | 6 | |
| National League | M. | W | D | L | goals | |||
| at home | 7 | 2 | 1 | 4 | 8 | : | 12 | |
| Away | 7 | 1 | 2 | 4 | 4 | : | 8 | |
| ∑ | 14 | 3 | 3 | 8 | 12 | : | 20 | |
| overall | M. | W | D | L | goals | |||
| at home | 8 | 2 | 2 | 4 | 9 | : | 13 | |
| Away | 9 | 2 | 2 | 5 | 9 | : | 13 | |
| Neutral Place | 0 | 0 | 0 | 0 | 0 | : | 0 | |
| ∑ | 17 | 4 | 4 | 9 | 18 | : | 26 | |
| FA Cup | |||||
| 1964/1965 | 2. Round | Wrexham AFC | - | Southport FC | 2:3 |
| 1962/1963 | 1. Round | Wrexham AFC | - | Southport FC | 3:2 |
| 1962/1963 | 1. Round | Southport FC | - | Wrexham AFC | 1:1 |
| National League | |||||
| 2016/2017 | 6. Round | Southport FC | - | Wrexham AFC | 3:2 (2:1) |
| 2016/2017 | 5. Round | Wrexham AFC | - | Southport FC | 1:0 (0:0) |
| 2015/2016 | 6. Round | Southport FC | - | Wrexham AFC | 3:2 (1:1) |
| 2015/2016 | 5. Round | Wrexham AFC | - | Southport FC | 0:1 (0:1) |
| 2014/2015 | 29. Round | Wrexham FC | - | Southport FC | 0:0 (0:0) |
| 2014/2015 | 27. Round | Southport FC | - | Wrexham FC | 0:1 (0:0) |
| 2013/2014 | 22. Round | Southport FC | - | Wrexham FC | 1:2 (1:1) |
| 2013/2014 | 14. Round | Wrexham FC | - | Southport FC | 1:0 (0:0) |
| 2012/2013 | 30. Round | Wrexham FC | - | Southport FC | 2:2 (1:1) |
| 2012/2013 | 17. Round | Southport FC | - | Wrexham FC | 1:4 (1:0) |
| 2011/2012 | 24. Round | Wrexham FC | - | Southport FC | 2:0 (1:0) |
| 2011/2012 | 10. Round | Southport FC | - | Wrexham FC | 0:0 (0:0) |
| 2010/2011 | 22. Round | Southport FC | - | Wrexham FC | 0:1 (0:1) |
| 2010/2011 | 10. Round | Wrexham FC | - | Southport FC | 2:1 (2:0) |
|
For games that were decided on penalties the score after 120 minutes will be included in the ranking |
England