Atalanta slipped up again in their bid for a first Serie A title with Saturday's goalless draw with Cagliari, as league leaders Napoli get set for a tough clash at Lazio.

Little happened in a drab stalemate in Bergamo which left third-placed Atalanta four points behind Napoli who take on Lazio in Rome later on Saturday.

Napoli are bidding to move four points ahead of champions and principle title rivals Inter Milan who travel to Turin on Sunday for a grudge match with Juventus.

Already hit with injuries including that of key attacker Ademola Lookman, Atalanta coach Gian Piero Gasperini dropped first teamers like Marten de Roon, Ederson and Charles De Ketelaere ahead of his team's return leg of a Champions League play-off with Club Brugge.

Atalanta trail that tie 2-1 after a hugely controversial penalty given against the Italians in stoppage of the first leg in Belgium on Wednesday night.

Gasperini was forced to bring on De Roon, Ederson and De Ketelaere in the second half as Atalanta struggled to break down resilient Cagliari who are 13th and five points above the relegation zone.

The closest the hosts game to taking the lead was when Marco Brescianini poked home from close range on the hour only for Stefan Posch to be penalised for a foul on Cagliari goalkeeper Elia Caprile.

Caprile also did well to keep out young striker Vanja Vlahovic who came on as a surprise replacement for Mateo Retegui just before Brescianini's goal was ruled out.

AC Milan host Verona in the day's late match hoping to bounce back from their Champions League defeat at Feyenoord.