| 2. Round | 01/08/2015 | FK Dukla Praha | - | Viktoria Plzeň | 1:0 |  |
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| 13. Round | 08/11/2015 | Baník Ostrava | - | Viktoria Plzeň | 0:4 | ||||
| 14. Round | 21/11/2015 | Viktoria Plzeň | - | FK Mladá Boleslav | 1:0 | ||||
| 15. Round | 30/11/2015 | FK Jablonec | - | Viktoria Plzeň | 0:1 | |
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| 16. Round | 06/12/2015 | Viktoria Plzeň | - | FK Dukla Praha | 3:0 | ||||
| 17. Round | 14/02/2016 | 1. FC Slovácko | - | Viktoria Plzeň | 1:2 | ||||
| 18. Round | 19/02/2016 | Viktoria Plzeň | - | FK Teplice | 1:0 | ||||
| 19. Round | 27/02/2016 | Sigma Olomouc | - | Viktoria Plzeň | 0:1 | ||||
| 20. Round | 06/03/2016 | Viktoria Plzeň | - | 1. FK Příbram | 4:0 | ||||
| 21. Round | 12/03/2016 | Viktoria Plzeň | - | Bohemians Praha 1905 | 2:0 | ||||
| 22. Round | 20/03/2016 | Slovan Liberec | - | Viktoria Plzeň | 0:1 | |
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| 23. Round | 02/04/2016 | Viktoria Plzeň | - | Vysočina Jihlava | 2:0 | ||||
| 24. Round | 09/04/2016 | FC Fastav Zlín | - | Viktoria Plzeň | 1:2 | ||||
| 25. Round | 17/04/2016 | Viktoria Plzeň | - | Zbrojovka Brno | 2:1 | |
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| 27. Round | 30/04/2016 | Viktoria Plzeň | - | Baník Ostrava | 2:0 | |
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| 28. Round | 07/05/2016 | FK Mladá Boleslav | - | Viktoria Plzeň | 2:0 |  |
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| 30. Round | 14/05/2016 | Slavia Praha | - | Viktoria Plzeň | 5:0 |
Czech Republic