| 1. Round | 28/08/2021 | US Triestina | - | Seregno | 0:0 |  |
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| 3. Round | 13/09/2021 | US Triestina | - | Piacenza Calcio | 2:2 | ||||
| 4. Round | 19/09/2021 | Calcio Padova | - | US Triestina | 2:0 | ||||
| 2. Round | 22/09/2021 | Juventus II | - | US Triestina | 2:1 | ||||
| 5. Round | 26/09/2021 | US Triestina | - | Calcio Lecco 1912 | 2:0 | ||||
| 6. Round | 29/09/2021 | AC Pro Sesto | - | US Triestina | 0:1 | ||||
| 7. Round | 03/10/2021 | US Triestina | - | UC AlbinoLeffe | 2:3 |
Italy