| 13. Round | 07/11/2021 | UC AlbinoLeffe | - | Pro Vercelli | 1:1 | ||||
| 14. Round | 14/11/2021 | Pro Vercelli | - | FC Legnago Salus | 0:1 | ||||
| 20. Round | 19/01/2022 | Calcio Lecco 1912 | - | Pro Vercelli | 0:0 | ||||
| 23. Round | 23/01/2022 | Pro Vercelli | - | Juventus II | 2:0 | ||||
| 24. Round | 29/01/2022 | Trento Calcio 1921 | - | Pro Vercelli | 0:0 | ||||
| 34. Round | 26/03/2022 | Pro Vercelli | - | US Pergolettese | 1:1 | ||||
| 35. Round | 02/04/2022 | Pro Vercelli | - | Calcio Padova | 0:1 | ||||
| 36. Round | 10/04/2022 | US Triestina | - | Pro Vercelli | 4:2 | ||||
| 38. Round | 24/04/2022 | Mantova 1911 SSD | - | Pro Vercelli | 3:0 |  |
Italy