| 19. Round | 23/02/1969 | SSC Palermo | - | Sampdoria | 1:0 | ||||
| 20. Round | 02/03/1969 | Sampdoria | - | AS Roma | 0:0 | ||||
| 21. Round | 09/03/1969 | AS Varese 1910 | - | Sampdoria | 0:0 | ||||
| 22. Round | 16/03/1969 | Sampdoria | - | ACF Fiorentina | 1:1 |  |
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| 23. Round | 23/03/1969 | Atalanta | - | Sampdoria | 0:0 | ||||
| 24. Round | 06/04/1969 | Sampdoria | - | Pisa SC | 1:2 | ||||
| 25. Round | 13/04/1969 | Hellas Verona | - | Sampdoria | 0:3 | ||||
| 26. Round | 20/04/1969 | Sampdoria | - | Bologna FC | 0:0 | ||||
| 29. Round | 11/05/1969 | Cagliari Calcio | - | Sampdoria | 0:0 | ||||
| 30. Round | 18/05/1969 | Sampdoria | - | Juventus | 1:1 |
Italy