| 1. Round | 21/09/1958 | AS Bari | - | Bologna FC | 0:0 | ||||
| 2. Round | 28/09/1958 | Bologna FC | - | Genoa CFC | 2:1 | ||||
| 3. Round | 05/10/1958 | Udinese Calcio | - | Bologna FC | 1:1 | ||||
| 4. Round | 12/10/1958 | Bologna FC | - | AS Roma | 1:0 | ||||
| 5. Round | 19/10/1958 | Calcio Padova | - | Bologna FC | 1:0 | ||||
| 6. Round | 26/10/1958 | Bologna FC | - | SPAL Ferrara | 3:2 | ||||
| 7. Round | 02/11/1958 | Torino FC | - | Bologna FC | 2:2 | ||||
| 8. Round | 16/11/1958 | Bologna FC | - | US Triestina | 0:2 | ||||
| 9. Round | 23/11/1958 | ACF Fiorentina | - | Bologna FC | 6:3 | ||||
| 10. Round | 30/11/1958 | Bologna FC | - | Inter | 2:2 | ||||
| 11. Round | 07/12/1958 | AC Lanerossi Vicenza | - | Bologna FC | 1:1 | ||||
| 12. Round | 21/12/1958 | Lazio Roma | - | Bologna FC | 2:1 | ||||
| 13. Round | 28/12/1958 | Bologna FC | - | SSC Napoli | 1:1 | ||||
| 14. Round | 04/01/1959 | Juventus | - | Bologna FC | 2:2 | ||||
| 15. Round | 11/01/1959 | Bologna FC | - | US Alessandria 1912 | 4:0 | ||||
| 16. Round | 18/01/1959 | Bologna FC | - | Sampdoria | 1:2 | ||||
| 31. Round | 24/05/1959 | Bologna FC | - | Juventus | 4:1 | ||||
| 32. Round | 28/05/1959 | US Alessandria 1912 | - | Bologna FC | 1:0 | ||||
| 33. Round | 31/05/1959 | Sampdoria | - | Bologna FC | 2:1 | ||||
| 34. Round | 07/06/1959 | Bologna FC | - | AC Milan | 1:1 |
Italy