| 2. Round | 31/07/2021 | KAS Eupen | - | RSC Anderlecht | 1:1 | ||||
| 3. Round | 07/08/2021 | KV Mechelen | - | KAS Eupen | 1:3 |  |
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| 4. Round | 14/08/2021 | KAS Eupen | - | Sint-Truidense VV | 2:1 | ||||
| 5. Round | 21/08/2021 | Oud-Heverlee Leuven | - | KAS Eupen | 1:4 | ||||
| 16. Round | 27/11/2021 | KAS Eupen | - | KV Kortrijk | 2:2 | ||||
| 17. Round | 04/12/2021 | KV Oostende | - | KAS Eupen | 2:1 | ||||
| 18. Round | 11/12/2021 | KAS Eupen | - | K Beerschot VA | 1:0 |
Guinea-Bissau
Portugal