| 12. Round | 05/11/2022 | Lucchese | - | US Alessandria 1912 | 1:2 | ||||
| 13. Round | 13/11/2022 | Fermana FC | - | US Alessandria 1912 | 0:0 | ||||
| 14. Round | 20/11/2022 | US Alessandria 1912 | - | ACN Siena 1904 | 0:1 | ||||
| 15. Round | 26/11/2022 | US Fiorenzuola | - | US Alessandria 1912 | 0:0 | ||||
| 16. Round | 29/11/2022 | US Alessandria 1912 | - | Olbia Calcio | 1:1 | ||||
| 17. Round | 03/12/2022 | Ancona 1905 | - | US Alessandria 1912 | 3:0 | ||||
| 18. Round | 10/12/2022 | US Alessandria 1912 | - | Aquila Montevarchi | 2:2 | ||||
| 21. Round | 08/01/2023 | Virtus Entella | - | US Alessandria 1912 | 4:2 |
Italy