| 1. Round | 13/09/1980 | Como Calcio | - | AS Roma | 0:1 | ||||
| 2. Round | 20/09/1980 | AS Roma | - | Brescia Calcio | 1:0 | ||||
| 3. Round | 27/09/1980 | Bologna FC | - | AS Roma | 1:1 | ||||
| 9. Round | 29/11/1980 | AS Roma | - | Udinese Calcio | 3:1 | ||||
| 18. Round | 21/02/1981 | AS Roma | - | Bologna FC | 1:1 | ||||
| 27. Round | 02/05/1981 | AS Roma | - | AC Perugia | 5:0 |
Italy