| Group B | 18/10/2020 | Danubio | - | Defensor Sporting | 0:0 | ||||
| Group B | 01/11/2020 | Defensor Sporting | - | Peñarol | 2:1 |  |
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| Group B | 11/11/2020 | Deportivo Maldonado | - | Defensor Sporting | 3:1 |  |
 |
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| Group B | 29/11/2020 | River Plate | - | Defensor Sporting | 1:1 | |
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| Group B | 13/01/2021 | Defensor Sporting | - | Boston River | 1:1 | |
Argentina
Italy