| 1. Round | 25/09/1960 | Torino FC | - | Sampdoria | 0:1 | ||||
| 7. Round | 13/11/1960 | Calcio Lecco 1912 | - | Sampdoria | 1:1 | ||||
| 8. Round | 20/11/1960 | Sampdoria | - | SSC Napoli | 0:0 | ||||
| 9. Round | 27/11/1960 | Inter | - | Sampdoria | 3:0 | ||||
| 23. Round | 12/03/1961 | Lazio Roma | - | Sampdoria | 0:1 |  |
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| 24. Round | 19/03/1961 | Sampdoria | - | Calcio Lecco 1912 | 1:0 | |
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| 25. Round | 26/03/1961 | SSC Napoli | - | Sampdoria | 1:0 | ||||
| 30. Round | 07/05/1961 | Calcio Padova | - | Sampdoria | 3:0 |
Italy