1. Round | 07/08/2021 | Sunderland AFC | - | Wigan Athletic | 2:1 | ||||
3. Round | 17/08/2021 | Wigan Athletic | - | Wycombe Wanderers | 1:1 | ||||
4. Round | 21/08/2021 | Charlton Athletic | - | Wigan Athletic | 0:2 | ||||
5. Round | 28/08/2021 | Wigan Athletic | - | Portsmouth FC | 1:0 | ||||
7. Round | 11/09/2021 | Wigan Athletic | - | Doncaster Rovers | 2:1 | ||||
8. Round | 18/09/2021 | Accrington Stanley | - | Wigan Athletic | 1:4 | ||||
10. Round | 28/09/2021 | Wigan Athletic | - | Sheffield Wednesday | 1:2 | ||||
14. Round | 19/10/2021 | Wigan Athletic | - | Milton Keynes Dons | 1:2 | ||||
19. Round | 23/11/2021 | Cambridge United | - | Wigan Athletic | 2:2 |