| 1. Round | 16/08/2011 | River Plate | - | Chacarita Juniors | 1:0 | ||||
| 2. Round | 20/08/2011 | Independiente Rivadavia | - | River Plate | 1:3 | ||||
| 3. Round | 27/08/2011 | River Plate | - | Desamparados de San Juan | 3:1 | ||||
| 4. Round | 03/09/2011 | Quilmes | - | River Plate | 1:1 | ||||
| 5. Round | 10/09/2011 | River Plate | - | Defensa y Justicia | 2:2 | ||||
| 6. Round | 17/09/2011 | Deportivo Merlo | - | River Plate | 0:0 | ||||
| 7. Round | 24/09/2011 | River Plate | - | Gimnasia de La Plata | 2:0 | ||||
| 8. Round | 01/10/2011 | Ferro Carril Oeste | - | River Plate | 0:0 | ||||
| 9. Round | 05/10/2011 | River Plate | - | Atlanta | 7:1 | ||||
| 10. Round | 09/10/2011 | Huracán | - | River Plate | 1:2 | ||||
| 11. Round | 15/10/2011 | Instituto de Córdoba | - | River Plate | 0:0 | ||||
| 12. Round | 29/10/2011 | River Plate | - | Aldosivi | 1:2 | ||||
| 13. Round | 05/11/2011 | Gimnasia de Jujuy | - | River Plate | 1:4 | ||||
| 14. Round | 13/11/2011 | River Plate | - | Atlético Tucumán | 0:2 | ||||
| 15. Round | 19/11/2011 | Guillermo Brown | - | River Plate | 1:4 | ||||
| 16. Round | 26/11/2011 | River Plate | - | Rosario Central | 1:1 | ||||
| 17. Round | 03/12/2011 | Boca Unidos | - | River Plate | 1:0 | ||||
| 18. Round | 12/12/2011 | River Plate | - | Patronato de Paraná | 1:0 |
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