| 18. Round | 15/12/2020 | Cercle Brugge | - | Sporting Charleroi | 3:4 | ||||
| 17. Round | 18/12/2020 | Sporting Charleroi | - | RSC Anderlecht | 1:0 |  |
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| 19. Round | 27/12/2020 | Royal Antwerp FC | - | Sporting Charleroi | 2:1 | ||||
| 30. Round | 09/01/2021 | KV Oostende | - | Sporting Charleroi | 3:2 | ||||
| 21. Round | 24/01/2021 | Standard Liège | - | Sporting Charleroi | 3:2 | ||||
| 22. Round | 27/01/2021 | Sporting Charleroi | - | Oud-Heverlee Leuven | 1:1 | ||||
| 23. Round | 30/01/2021 | KV Kortrijk | - | Sporting Charleroi | 1:3 | ||||
| 24. Round | 07/02/2021 | Sporting Charleroi | - | SV Zulte Waregem | 1:1 | ||||
| 27. Round | 20/02/2021 | Waasland-Beveren | - | Sporting Charleroi | 1:1 | ||||
| 28. Round | 26/02/2021 | Sporting Charleroi | - | KRC Genk | 1:2 | ||||
| 29. Round | 05/03/2021 | Sporting Charleroi | - | Sint-Truidense VV | 0:0 | ||||
| 32. Round | 04/04/2021 | Sporting Charleroi | - | Royal Excel Mouscron | 1:1 | ||||
| 31. Round | 07/04/2021 | K Beerschot VA | - | Sporting Charleroi | 2:1 | ||||
| 33. Round | 10/04/2021 | KAA Gent | - | Sporting Charleroi | 4:0 | ||||
| 34. Round | 17/04/2021 | Sporting Charleroi | - | KAS Eupen | 2:3 | |
Poland