| 5. Round | 26/09/2021 | Giana Erminio | - | UC AlbinoLeffe | 0:1 | ||||
| 8. Round | 10/10/2021 | UC AlbinoLeffe | - | AC Renate | 2:3 | ||||
| 13. Round | 07/11/2021 | UC AlbinoLeffe | - | Pro Vercelli | 1:1 | ||||
| 14. Round | 14/11/2021 | Calcio Lecco 1912 | - | UC AlbinoLeffe | 2:3 | ||||
| 15. Round | 21/11/2021 | AC Pro Sesto | - | UC AlbinoLeffe | 0:0 | ||||
| 16. Round | 29/11/2021 | UC AlbinoLeffe | - | Piacenza Calcio | 2:3 | ||||
| 27. Round | 16/02/2022 | AC Renate | - | UC AlbinoLeffe | 0:2 | ||||
| 22. Round | 23/02/2022 | UC AlbinoLeffe | - | US Fiorenzuola | 0:0 | ||||
| 29. Round | 27/02/2022 | Juventus II | - | UC AlbinoLeffe | 1:1 |  |
|||
| 32. Round | 16/03/2022 | Pro Vercelli | - | UC AlbinoLeffe | 1:0 | ||||
| 33. Round | 20/03/2022 | UC AlbinoLeffe | - | Calcio Lecco 1912 | 2:1 | ||||
| 36. Round | 10/04/2022 | UC AlbinoLeffe | - | Virtus Verona | 0:0 | ||||
| 37. Round | 16/04/2022 | FC Legnago Salus | - | UC AlbinoLeffe | 1:3 | |
|||
| 38. Round | 24/04/2022 | UC AlbinoLeffe | - | Trento Calcio 1921 | 1:3 |
Italy