3. Round | 28/08/2022 | US Lecce | - | Empoli FC | 1:1 | ||||
6. Round | 11/09/2022 | US Lecce | - | AC Monza | 1:1 | ||||
7. Round | 16/09/2022 | US Salernitana 1919 | - | US Lecce | 1:2 | ||||
8. Round | 02/10/2022 | US Lecce | - | US Cremonese | 1:1 | ||||
10. Round | 17/10/2022 | US Lecce | - | ACF Fiorentina | 1:1 | ||||
11. Round | 23/10/2022 | Bologna FC | - | US Lecce | 2:0 | ||||
12. Round | 29/10/2022 | US Lecce | - | Juventus | 0:1 | ||||
14. Round | 09/11/2022 | US Lecce | - | Atalanta | 2:1 | ||||
15. Round | 12/11/2022 | Sampdoria | - | US Lecce | 0:2 |