| 25. Round | 15/02/2025 | Sampdoria [Youth] | - | AS Roma [Youth] | 0:2 | ||||
| 26. Round | 19/02/2025 | Empoli FC [Youth] | - | Sampdoria [Youth] | 1:1 |  |
|||
| 27. Round | 23/02/2025 | US Lecce [Youth] | - | Sampdoria [Youth] | 3:1 | ||||
| 28. Round | 02/03/2025 | Sampdoria [Youth] | - | Cesena FC [Youth] | 1:1 | ||||
| 29. Round | 09/03/2025 | Bologna FC [Youth] | - | Sampdoria [Youth] | 2:0 | ||||
| 30. Round | 15/03/2025 | Sampdoria [Youth] | - | US Cremonese [Youth] | 2:2 | ||||
| 31. Round | 31/03/2025 | AC Milan [Youth] | - | Sampdoria [Youth] | 1:2 | ||||
| 32. Round | 05/04/2025 | Sampdoria [Youth] | - | Cagliari Calcio [Youth] | 0:3 | ||||
| 34. Round | 22/04/2025 | Sampdoria [Youth] | - | Torino FC [Youth] | 1:3 | ||||
| 35. Round | 27/04/2025 | Atalanta [Youth] | - | Sampdoria [Youth] | 4:1 | ||||
| 37. Round | 10/05/2025 | Inter [Youth] | - | Sampdoria [Youth] | 1:0 |
Bulgaria