| 15. Round | 05/02/2022 | Venezia FC [Youth] | - | Virtus Entella [Youth] | 3:0 |  |
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| 16. Round | 12/02/2022 | Virtus Entella [Youth] | - | AC Reggiana 1919 [Youth] | 1:0 |  |
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| 14. Round | 15/02/2022 | Virtus Entella [Youth] | - | L.R. Vicenza [Youth] | 3:0 | |
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| 17. Round | 19/02/2022 | Udinese Calcio [Youth] | - | Virtus Entella [Youth] | 1:0 | ||||
| 18. Round | 26/02/2022 | Virtus Entella [Youth] | - | US Cremonese [Youth] | 0:1 | |
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| 20. Round | 12/03/2022 | AC Monza [Youth] | - | Virtus Entella [Youth] | 3:2 | |
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| 21. Round | 19/03/2022 | Virtus Entella [Youth] | - | Brescia Calcio [Youth] | 1:3 | |
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| 22. Round | 26/03/2022 | Como 1907 [Youth] | - | Virtus Entella [Youth] | 2:2 | |
Senegal