| 1. Round | 21/08/2022 | Sampdoria [Youth] | - | Hellas Verona [Youth] | 0:0 | ||||
| 2. Round | 26/08/2022 | Sampdoria [Youth] | - | AC Milan [Youth] | 2:1 | ||||
| 3. Round | 01/09/2022 | US Lecce [Youth] | - | Sampdoria [Youth] | 0:0 | ||||
| 7. Round | 08/10/2022 | Juventus [Youth] | - | Sampdoria [Youth] | 3:1 | ||||
| 8. Round | 15/10/2022 | Cagliari Calcio [Youth] | - | Sampdoria [Youth] | 1:1 | ||||
| 9. Round | 23/10/2022 | Sampdoria [Youth] | - | Udinese Calcio [Youth] | 0:1 | ||||
| 12. Round | 13/11/2022 | SSC Napoli [Youth] | - | Sampdoria [Youth] | 1:1 |  |
Italy