| 1. Round | 20/08/2022 | PAOK Saloniki | - | Panetolikos | 1:0 | ||||
| 3. Round | 04/09/2022 | Aris Saloniki | - | PAOK Saloniki | 0:0 |  |
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| 5. Round | 18/09/2022 | OFI Heraklion | - | PAOK Saloniki | 1:1 | ||||
| 6. Round | 02/10/2022 | PAOK Saloniki | - | Panathinaikos | 1:2 | ||||
| 7. Round | 09/10/2022 | Levadiakos | - | PAOK Saloniki | 1:1 | ||||
| 8. Round | 17/10/2022 | Olympiakos Piraeus | - | PAOK Saloniki | 1:2 |  |
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| 9. Round | 23/10/2022 | PAOK Saloniki | - | Asteras Tripolis | 2:2 | ||||
| 10. Round | 30/10/2022 | AEK Athen | - | PAOK Saloniki | 2:0 | ||||
| 11. Round | 05/11/2022 | PAOK Saloniki | - | PAS Giannina | 2:0 | |
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| 12. Round | 10/11/2022 | Ionikos Nikea | - | PAOK Saloniki | 0:3 | ||||
| 13. Round | 13/11/2022 | PAOK Saloniki | - | Volos NFC | 3:0 | ||||
| 14. Round | 22/12/2022 | Panetolikos | - | PAOK Saloniki | 0:2 | ||||
| 25. Round | 05/03/2023 | PAOK Saloniki | - | Ionikos Nikea | 6:0 | ||||
| 26. Round | 12/03/2023 | Volos NFC | - | PAOK Saloniki | 0:1 |
Belgium
