| 24. Round | 07/02/2022 | US Salernitana 1919 | - | Spezia Calcio | 2:2 | ||||
| 25. Round | 13/02/2022 | Genoa CFC | - | US Salernitana 1919 | 1:1 |  |
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| 26. Round | 19/02/2022 | US Salernitana 1919 | - | AC Milan | 2:2 | ||||
| 27. Round | 26/02/2022 | US Salernitana 1919 | - | Bologna FC | 1:1 | ||||
| 28. Round | 04/03/2022 | Inter | - | US Salernitana 1919 | 5:0 | ||||
| 30. Round | 20/03/2022 | Juventus | - | US Salernitana 1919 | 2:0 | ||||
| 31. Round | 02/04/2022 | US Salernitana 1919 | - | Torino FC | 0:1 | ||||
| 32. Round | 10/04/2022 | AS Roma | - | US Salernitana 1919 | 2:1 | ||||
| 33. Round | 16/04/2022 | Sampdoria | - | US Salernitana 1919 | 1:2 | |
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| 34. Round | 24/04/2022 | US Salernitana 1919 | - | ACF Fiorentina | 2:1 | ||||
| 35. Round | 02/05/2022 | Atalanta | - | US Salernitana 1919 | 1:1 | ||||
| 20. Round | 05/05/2022 | US Salernitana 1919 | - | Venezia FC | 2:1 | ||||
| 36. Round | 08/05/2022 | US Salernitana 1919 | - | Cagliari Calcio | 1:1 | ||||
| 37. Round | 14/05/2022 | Empoli FC | - | US Salernitana 1919 | 1:1 | ||||
| 38. Round | 22/05/2022 | US Salernitana 1919 | - | Udinese Calcio | 0:4 |
Italy