| 13. Round | 06/03/2021 | Cagliari Calcio [Youth] | - | Sampdoria [Youth] | 1:1 | ||||
| 14. Round | 09/03/2021 | Sampdoria [Youth] | - | ACF Fiorentina [Youth] | 4:2 | ||||
| 15. Round | 12/03/2021 | Torino FC [Youth] | - | Sampdoria [Youth] | 0:3 | ||||
| 16. Round | 20/03/2021 | Sampdoria [Youth] | - | Inter [Youth] | 2:1 | ||||
| 17. Round | 03/04/2021 | Lazio Roma [Youth] | - | Sampdoria [Youth] | 1:4 | ||||
| 18. Round | 10/04/2021 | Sampdoria [Youth] | - | Genoa CFC [Youth] | 3:1 | ||||
| 19. Round | 18/04/2021 | Empoli FC [Youth] | - | Sampdoria [Youth] | 2:2 | ||||
| 20. Round | 26/04/2021 | Sampdoria [Youth] | - | Juventus [Youth] | 1:2 | ||||
| 21. Round | 01/05/2021 | SPAL 2013 Ferrara [Youth] | - | Sampdoria [Youth] | 2:1 | ||||
| 25. Round | 26/05/2021 | Sampdoria [Youth] | - | Sassuolo Calcio [Youth] | 1:1 | ||||
| 28. Round | 09/06/2021 | Sampdoria [Youth] | - | Cagliari Calcio [Youth] | 1:0 | ||||
| 30. Round | 16/06/2021 | Sampdoria [Youth] | - | Torino FC [Youth] | 5:0 |
Bosnia-Herzegovina